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Keywords Affinity maturation;Genetically engineered antibody;Mutagenesis; 亲和力成熟;基因工程抗体;突变;
The cluster operation divided the population into subpopulations for the stage of selection and reproduction, thus improving the variety of antibodies and affinity maturation. 通过聚类将抗体群分成多个子种群来实现其克隆选择策略，加速克隆扩增，从而提高抗体成熟力及亲和性。
The algorithm is inspired by the mechanism in which a kind of antibody can identify multi-epitope of an antigen and gradually accomplish affinity maturation in the evolutionary process. 算法的主要算子包括正选择、记忆细胞产生、超变异和抗体相似性抑制。
Keywords hepatocyte growth factor/scatter factor;phage display antibody library;affinity maturation;internalizing antibody; 肝细胞生长因子受体;噬菌体抗体库;亲和力成熟;内化抗体;
Keywords hepatocyte growth factor receptor （Met）;phage-displayed antibody library;affinity maturation;internalized antibody; 肝细胞生长因子受体;噬菌体抗体库;亲和力成熟;内化抗体;
Keywords affinity chromatography;heparin;antithrombin III; 亲和层析;肝素;抗凝血酶III;
Keywords affinity membrane;endotoxin removal;histidine;polymyxin B; 亲和膜;内毒素;组氨酸;粘多菌素B;
Keywords affinity;colour fixation rete;reactive dyes;compatibility; 亲和力;固色速率;配伍性;日晒牢度;
Keywords affinity membrane;cellulose ovotransferrin（OTf）;lysozyme（Lys）; 亲和膜;纤维素;卵转铁蛋白;溶菌酶;
Keywords affinity membrane;cellulose;metal-chelated;Ovotransferrin;Lysozyme; 亲和膜;纤维素;金属螯合;卵转铁蛋白;溶菌酶;
affinity maturation 亲和力成熟
Keywords affinity chromatography;Izumo;immunocontraception;sperm-egg fusion;sperm antigen; 精卵融合;免疫避孕;精子抗原;亲和层析;
Keywords affinity membrane;combinatorial chemistry;aminomethylation polysulfone;synthesize;acyl chlorine;sorption; 亲和膜;组合化学;胺甲基化聚砜;酰氯;吸附;
Keywords affinity partition;aqueous two-phase system;metal chelating;soybean hull peroxidase; 亲和分配;双水相系统;金属螯合;豆壳过氧化物酶;
Keywords affinity partition;hydroxyl group;thionyl chloride;triethylamine;polyethylene glycol; 亲和分配;羟基;二氯亚砜;三乙胺;聚乙二醇;
Keywords affinity membrane;polyethyleneimine;cellulose acetate;blend;microfiltration membrane; 亲和膜;聚乙烯基亚胺;醋酸纤维素;共混;微孔滤膜;
Keywords Affinity membrane;Bilirubin;Cibacron blue F3GA;Trimethylamine;Graft polymerization;preirradiation; 亲和膜;胆红素;聚丙烯;辛巴蓝;三甲胺;接枝聚合;预辐射;
Keywords Affinity capillary electrophoresis;Theophylline;Binding constant;Human serum albumin; 关键词亲和毛细管电泳法;茶碱;结合常数;人血清白蛋白;
Keywords affinity protein purification;expanded bed;velocity voidage relationship;particulate fluidization; 亲和层析分离;膨胀床;速度-液含率;散式流化;
Keywords Affinity capillary electrophoresis;trimebutine maleate;chiral separation; 亲和毛细管电泳法;马来酸曲美布汀;手性分离;